Skip to main content
Store MI

Mason City Hy-Vee Drugstore

 Save this as My Hy-Vee

At the intersection of Highway 122 and Crescent Drive, across from the hospital.

Open 7 a.m. - 10 p.m. Monday - Thursday
7 a.m. - 11 p.m. Friday & Saturday
9 a.m. - 9 p.m. Sunday

875 Fourth Street SW
Mason City, IA 50401
Google Maps
Email Subscriptions

Get emails from our store

Sign up


Get the latest Hy-Vee Deals

See sale items

Aisles Online Grocery Shopping

For pick up or delivery.

Start Shopping

Department Hours

Garden Center: Open late April through late June
Pharmacy: 8 a.m. to 9 p.m. Monday-Friday
9 a.m. to 6 p.m. Saturday
10 a.m. to 6 p.m. Sunday
Wine & Spirits: 7 a.m. to 10 p.m. Monday-Thursday
7 a.m. to 11 p.m. Friday & Saturday
9 a.m. to 9 p.m. Sunday

Store News

Holiday Closing Times

View our hours of operation during the holiday season.  Read more.

Hy-Vee Drugstore Wins Globe Gazette Readers Choice Award

Hy-Vee Drugstore won the Globe Gazette Readers Choice Award for Best Pharmacy. We would like to thank all our customers fo your support and dedication!  Read more.

More Than A Pharmacy

Hy-Vee Drugstore offers flu and shingle vaccines to the public.  Read more.

View All Store News
Events Calendar
Dietitian Hours

12/13/2018 8:00 a.m. - 4:00 p.m.
Dietitian Sara will be available to answer any of your nutrition questions! Read more.

Dietitian Sampling Event

12/13/2018 1:00 p.m. - 4:00 p.m.
Hy-Vee Drugstore Dietitian, Sara, will demo a healthy food item from 1 p.m. to 4 p.m.! Read more.

View All Events

No matter the occasion, casual or formal, your Hy-Vee caterers have you covered.

Browse Our Selections