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Mason City Hy-Vee Drugstore

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At the intersection of Highway 122 and Crescent Drive, across from the hospital.

Open 7 a.m. - 10 p.m. Monday - Thursday
7 a.m. - 11 p.m. Friday & Saturday
9 a.m. - 9 p.m. Sunday
Closed Christmas Day. Reopening December 26th 7 a.m.

875 Fourth Street SW
Mason City, IA 50401
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Phone Numbers:
Store: 641-424-4181
Department Phone Numbers
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Online Refills
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Department Hours
Dietitian: Stop in to see her weekly schedule or set up an appointment.
Garden Center: Open late April through late June
Pharmacy: 8 a.m. to 9 p.m. Monday-Friday; 9 a.m. to 6 p.m. Saturday; 10 a.m. to 6 p.m. Sunday
Wine & Spirits: 7 a.m. to 10 p.m. Monday-Thursday; 7 a.m. to 11 p.m. Friday & Saturday; 9 a.m. to 9 p.m. Sunday
Store News
Holiday Closing Times

View our hours of operation during the holiday season.  Read more.

Hy-Vee Drugstore Wins Globe Gazette Readers Choice Award

Hy-Vee Drugstore won the Globe Gazette Readers Choice Award for Best Pharmacy. We would like to thank all our customers fo your support and dedication!  Read more.

More Than A Pharmacy

Hy-Vee Drugstore offers flu and shingle vaccines to the public.  Read more.

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Calendar of Events
No Upcoming Events
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Dietitian services
At Your Service

If you have a question or need an informed opinion, just ask your Hy-Vee dietitian.

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Department Features

Learn more about the departments and services offered at your Mason City Hy-Vee Drugstore and the store management.

Hy-Vee Floral

No matter what your occasion is, casual to formal, your Hy-Vee caterers do it. Browse our selections for your next special event.

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