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Ames Hy-Vee Drugstore

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At the intersection of Main and Clark, two blocks west of Highway 69/Duff Ave.

Open 7 a.m.-8 p.m Monday-Friday; 9 a.m.-5 p.m. Saturday; 10 a.m.-4 p.m. Sunday. Closed Thanksgiving Day , and Christmas Day.
New Year's Day, Easter, Memorial Day, 4th of July &Labor Day open 10 a.m.-4 p.m.

500 Main Street
Ames, IA 50010
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Phone Numbers:
Store: 515-233-9855
Department Phone Numbers
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Online Refills
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Department Hours
Hy-Vee Drugstore Clinic: 8 a.m. to 7 p.m. Mon.-Fri.; 8 a.m. to 1 p.m. Sat.; Closed Sun.
Pharmacy: 8 a.m. to 8 p.m. Mon-Fri.; 9 a.m. to 5 p.m. Sat.; 10 a.m. to 4 p.m. Sun. Closed holidays.
Store News
May Wine & Spirits and Gourmet Food Tasting

Mark your calendars for Thursday, May 1st, from 4:30-6:30 p.m. for our monthly Wine & Spirits and Gourmet Food Tasting. "A Taste of Hy-Vee"  Read more.

Easter Hours

We will be open on Easter, April 20, for all your pharmacy and drugstore needs.  Read more.

Meet Our New Store Director

Stop in and welcome our new store director, Fred French.  Read more.

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Calendar of Events
Easter Hours 2014

4/20/2014 10:00 a.m. - 4:00 p.m.
We will be open on Easter, April 20, from 10:00 a.m - 4:00 p.m. Read more.

Monthly Wine & Spirits and Gourmet Food Tasting

5/1/2014 4:30 p.m. - 6:30 p.m.
"A Taste of Hy-Vee," a Cinco de Mayo pre-party. Read more.

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Dietitian services
At Your Service

If you have a question or need an informed opinion, just ask your Hy-Vee dietitian.

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Department Features

Learn more about the departments and services offered at your Ames Hy-Vee Drugstore and the store management.

Hy-Vee Floral

No matter what your occasion is, casual to formal, your Hy-Vee caters to it. Browse our selections for your next special event.

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