Headache, flushing, dry eyes, or dry lips/skin may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To relieve dry eyes, you may use a lubricating eye ointment or tear replacement eye drops. Ask your pharmacist for details. If you wear contact lenses and get dry eyes, you may need to wear glasses while using this medication.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these serious side effects occur: mental/mood changes (such as depression, anxiety, thoughts of suicide), back/joint/muscle pain.
Stop taking alitretinoin and tell your doctor right away if any of these serious side effects occur: abdominal pain, bloody/severe diarrhea, bleeding from the rectum, persistent/severe headache, vision changes (such as blurred/double vision, decreased vision), persistent nausea/vomiting.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.